An experimental study in mice shows that chronic consumption of a high-salt diet disrupts gut microbiota, elevates brain inflammation in the hippocampus, and impairs recognition memory and anxiety-like behaviors. The researchers link microbial shifts to changes in hippocampal gene expression and neuronal loss, while noting that causation remains unproven and suggesting fecal transplant experiments for future work.
The findings illustrate the gut-brain axis as a pathway through which diet and microbial ecology can influence cognitive and emotional processes relevant to psychology. They also demonstrate how behavioral tests in animals map onto underlying neural and inflammatory changes, highlighting the interconnectedness of physiology and mental function.
Article Title: A high-salt diet triggers inflammation and memory loss by altering the microbiome
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