Lmst

It's like certain thoughts certain topics are really inflammatory for me...
I dont know if its necessary to have them...

#blog #thoughtsfeelings #neuroinflammation

This briefing holds relevance for mental health professionals, including psychotherapists, social workers, and counselors, by highlighting a repair mechanism in the spinal cord that operates via lesion-remote astrocytes. These astrocytes release CCN1 to reprogram immune cells for debris clearance, offering a cellular lens on neuroinflammatory processes involved in recovery. Such insights can inform understanding of recovery trajectories and psychological adaptation for patients facing paralysis, stroke, or MS, and may influence future approaches to holistic care.

Article Title: Scientists discover hidden brain cells that help heal spinal cord injuries

Link to Science Daily Mind-Brain News: https://ift dot tt/j13Pi6G

#SpinalCordInjury #Astrocytes #NeuralRepair #Neuroinflammation #CCN1

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🧠 Alzheimer Microglia — Jan 2026

• Distinct microglial states emerge with disease-specific gene programs
• TREM2 and metabolic wiring shape microglial function in AD
• Environmental and infectious signals modulate neuroinflammation
• Exosomes, miRNAs, and Aβ disaggregation explored as therapeutic angles

https://pir.sh/z0odQxl1LO

#Alzheimers #Microglia #Neuroinflammation #Neuroscience

🧠 Microglia — Jan 2026

• TREM2 and metabolic rewiring influence neurodegeneration
• Infectious and inflammatory triggers amplify CNS immune signaling
• Microglia-targeted therapies gain momentum in neurodegenerative disease

https://pir.sh/qmxdxQyayp

#Microglia #Neuroinflammation #Neurodegeneration

An experimental study in mice shows that chronic consumption of a high-salt diet disrupts gut microbiota, elevates brain inflammation in the hippocampus, and impairs recognition memory and anxiety-like behaviors. The researchers link microbial shifts to changes in hippocampal gene expression and neuronal loss, while noting that causation remains unproven and suggesting fecal transplant experiments for future work.

The findings illustrate the gut-brain axis as a pathway through which diet and microbial ecology can influence cognitive and emotional processes relevant to psychology. They also demonstrate how behavioral tests in animals map onto underlying neural and inflammatory changes, highlighting the interconnectedness of physiology and mental function.

Article Title: A high-salt diet triggers inflammation and memory loss by altering the microbiome

Link to PsyPost Article: ift dot tt/8DjBEyK

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#GutBrainAxis #GutMicrobiome #Neuroinflammation #MemoryLoss #HighSaltDiet

Notable for mental health professionals, including psychotherapists, counselors, and social workers, the article highlights two key points: (1) neurons actively respond to amyloid beta and inflammatory cues via a shared receptor, triggering synapse loss; (2) targeting this receptor could offer protective strategies for memory beyond current amyloid-focused therapies.

Article Title: Alzheimer’s may trick the brain into erasing its own memories

Link to Science Daily Mind-Brain News: https://ift dot tt/N2fhAIS

#Alzheimers #MemoryLoss #SynapsePruning #Neuroinflammation #Amyloid

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Aspirin and N-acetylcysteine co-administration markedly inhibit chronic ethanol intake and block relapse binge drinking: Role of neuroinflammation-oxidative stress self-perpetuation [2019]
https://pubmed.ncbi.nlm.nih.gov/31733014/

link to full text:
https://repositorio.udd.cl/server/api/core/bitstreams/19b18abc-323a-4be6-9fa9-b084fa5ec1ab/content

~
Female only study ('Adult female rats, Wistar-derived, bred for over 90 generations as alcohol consumers').

#neuroinflammation #glutamate #AlcoholUseDisorder #NAC #aspirin

Repetitive transcranial magnetic stimulation alleviates glial activation through suppressing HMGB1/TLR4 pathway in a rat model of Parkinson’s disease [2023]
https://doi.org/10.1007/s11033-023-08561-8

"This study showed that rTMS might be a promising method for alleviating neuroinflammation in PD rat models, and the effects might be mediated through the downregulation of the HMGB1/TLR4 pathway."

#Parkinsons #rTMS #TLR4 #neuroinflammation

#Kulturkampf #Medizin

.. promise in modulating numerous processes associated with #neurodegenerativediseases, #cancer, #epilepsy, and #traumaticbraininjury [Table 1]. In addition, the #ECS is known to influence #neuroplasticity, #apoptosis, #excitotoxicity, #neuroinflammation, and #cerebrovascularbreakdown associated with #stroke and #trauma.[105]

https://pmc.ncbi.nlm.nih.gov/articles/PMC5938896/

#WEEDMoB #Hanfgeschichten #hanf #hemp #marijuana
#Streeck 🙏 #NinaWarken 🙏
Herr #Merz #Söder #Klingbeil 😀 #Cannabis

Phytocannabinoids CBD and Δ9-THC
In addition to the phytocannabinoid Δ9-THC, it is estimated that the cannabis plant consists of over 400 chemical entities, of which more than 60 of them are phytocannabinoid compounds. Some of these compounds have been identified as acting uniquely on both CB1 and CB2 receptors separately and simultaneously, and/or to inhibit or activate receptor functions. CBD, like Δ9-THC, is a major phytocannabinoid accounting for up to 40% of the plant's extract. CBD was first discovered in 1940 more than 20 years before Δ9-THC.[104,105] Until recently, Δ9-THC dominated cannabis research. All classes of phytocannabinoid compounds found in marijuana and hemp, including Δ9-THC and CBD, are derived from various changes to base molecular structure of cannabigerol-type compounds [Figure 1].[34,49]

Myeloid cells drive #neuroinflammation in #MultipleSclerosis by promoting immune activation in the #CentralNervousSystem. This study identifies SLAMF5 as a key myeloid receptor that regulates this process, showing that its blockade reduces disease progression @PLOSBiology https://plos.io/3Vb7xhx