#Lupus and LupusNephritis (LN) can be diagnosed TOGETHER for as many as 30% of lupus patients. As many as 60% of Lupus #SLE patients will see kidney impact.
YOU deserve better!
Ask your provider for treatments leading to #lupusremission as outlined by the American College of Rheumatology. #shareddecisionmaking.
Loss-of-function mutations in PLD4 linked to SLE:
🔬 PLD4 mutations led to high TLR7/9 activation
🔬 5 patients showed reduced exonuclease activity
🔬 Effective baricitinib treatment in mice
#SLE #Genetics #Inflammation #Pub2Post
https://tnyp.me/vwTf6xf5/m
Hey, I caught an interview with one of these researchers yesterday on #CBC's #QuirksAndQuarks.
This could be excellent news for eventually preventing future humans from having to live with #Lupus! ❤️
(Alas, it sounds like there is no anticipated way to make this learning applicable to people already infected with EBV and/or dx'd with Lupus 😢).
https://med.stanford.edu/news/all-news/2025/11/lupus-epstein-barr.html
❄️ Schneeflöckchen, Weißröckchen… Heute kommt unser letzter #CharitéScienceShot geschneit. Wir verabschieden uns von einem lehrreichen 2025 und wünschen eine besinnliche Adventszeit! Unser lieblicher Stern wohnt übrigens nicht in den Wolken. Sondern?
#Wissenschaft #Forschung #Medizin #ScienceMastodon #Fotografie #photography #Lupus #SLE
💪 #SLE2026 website is live 💪
The #ACM #SIGPLAN International Conference on #Software #Language Engineering (#SLE) is devoted to the principles of software languages: their design, their implementation, and their evolution. And of course, the role #AI can play in all these tasks.
Start preparing your:
☑️ Research Papers
☑️ New ideas Papers
☑️ Tool Papers
I can't think of a better excuse to escape your never-ending Christmas feasts 😉 🎅⛄
As a follow-up to this thread: there is now also an editorial emphasizing the value of our resource for the community: https://www.embopress.org/doi/full/10.1038/s44318-025-00633-8
Special emphasis on the non-canonical functions of the human complement system. #SLE #Ntermini #EMBOJournal
Three women—a single mom with a high-risk pregnancy; a young woman with deteriorating lupus; a widow with a severe dental condition—are facing medical emergencies.
No goal today (I can’t type them anymore, and they don’t move, anyway). ANYTHING helps. Click WEEKLY to sustain hope.
https://chuffed.org/project/hope-giving-circle
@mutualaid @palestine
#MutualAid #MutualAidRequest #Gaza #Palestine #Lupus #SLE
Looking at proteolytis in human plasma, we observed a lot of cleavages in complement C3, with known cleavages for C3a, C3b, and C3(d)g - but also a yet not deeply investigated cleavage at pos. 1514, which represented for us a quite intriguing lupus-enriched cleavage, thus we named it C3-LHF1 for complement "C3 Lupus Human Fragment 1" #C3 #Complement #LHF1 #SLE #Lupus 3/n
After a looong journey, I can present you the results of a deep & thorough investigation of human plasma proteolysis by mass spec: SLE N-terminomics paper with a complement C3 fragment(s) is out now in EMBOJ: https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8 - highlights: a nice resource on proteolytically processed N-termini in human plasma of healthy & SLE patients, with a lot of complement bonus for all interested scientists. #SLE #Science #Proteomics #TeamMassSpec #InflammatoryDisease #LupusResearch #C3 #LHF1 1/10
Der Mann hat was neues für #Lupus gefunden - oder wie @kabalak selbst sagen würde:
In conclusion, this study uncovers a new dimension of immune crosstalk: a proteolytic plasma network that generates immunoactive fragments with intrinsic self-regulatory capabilities to modulate #inflammation and tissue injury in complex disease contexts. Deciphering these immunoactivities may pave the way for innovative diagnostic and therapeutic strategies in complement-driven pathologies, potentially benefiting a wide range of inflammatory and autoimmune diseases.
#AutoimmuneDiseases #InflammatoryDisease #Science #SLE #proteomics #MassSpec #TeamMassSpec #LupusResearch
https://www.embopress.org/doi/full/10.1038/s44318-025-00598-8
Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 081756Z 02009KT 10SM BKN030 OVC037 13/07 A2986 RMK AO2 SLP111 T01330072 10133 20083 58001” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 081756Z 02009KT 10SM BKN030 OVC037 13/07 A2986 RMK AO2 SLP111 T01330072 10133 20083 58001” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vii3
Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 011756Z COR 18005KT 5SM -RA BR SCT041 SCT060 OVC080 16/13 A2986 RMK AO2 SLP112 P0002 60007 T01560133 10156 20139 51010 $” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 011756Z COR 18005KT 5SM -RA BR SCT041 SCT060 OVC080 16/13 A2986 RMK AO2 SLP112 P0002 60007 T01560133 10156 20139 51010 $” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vii3
#openSUSE's Leap 16 and Leap Micro adopt a 24-month lifecycle, sharing a binary core with #SLE. Stability, predictability, and modern updates included. #opensource #Linux https://news.opensuse.org/2025/09/03/leap-16-doubles-support/
Even Aushra Augustanavichute in her work on the concept of socionics wrote that this is still raw, but they are open to dialogue in the world. Especially if you consider that they had only a few descriptions for SLE.
#socionics #psychosophy #Artist #SLE
https://www.olnba.com/771108/ グループフェーズ|コート・d’ivoire v sierra leone |フルバスケットボールゲーム| FIBA U16 Afrobasket 2025 ##FIBA #04.09.2025 #Basketball #CivVSLE04.09.2025 #CoteD'Ivoire（Civ） #FIBAU16Afrobasket #FIBAU16Afrobasket2025 #sle #コートd'ivoire（civ） #コートジボワール #シエラレオネ #シエラレオネ（SLE） #シビング #バスケットボール #バスケットボールライブストリーム #フルゲーム #ライブ #ライブストリーム
Aviation weather for McNary Field airport in Salem area (USA) is “KSLE 231856Z 34005KT 10SM CLR 30/09 A2988 RMK AO2 SLP115 T03000094” : See what it means on https://www.bigorre.org/aero/meteo/ksle/en #salem #usa #mcnaryfieldairport #ksle #sle #metar #aviation #aviationweather #avgeek #airport vl
@CannaParts @bagder
Does #suse only distribute #curl für #opensuse and #sle #sles or do they use it for "production" and running their infrastruktur and actively working with it etc.pp.? 🤔 I know that their #supportconfig uses curl for uploading support data for support…
😭
Then they lost a private SLE license...
Even I'm using mainly #Tumbleweed... I hav... uhh... had a #SLE subscription since the beginning...
