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IMAGINATION or REALITY? https://lindahourihan.wordpress.com/2026/02/04/imagination-or-reality/ #Body, #Brain, #BrainHealth, #BrainLearnesByRepetition, #BrainScan, #Emotional, #Emotions, #Health, #HowDoesTheBrainLearn, #Identification, #Identity, #Imagination, #ImaginedExperience, #Manifestation, #Mental-health, #Mind, #MotorCortex, #NeuralHabits, #Neuroscience, #PersonalDevelopment, #PersonalGrowth, #RealExperience, #Reality, #RewireBrain, #Science, #Spirit, #Thinking, #Visualization

There is a new episode on the #TheoreticalNeurosciencePodcast on low-dimensional #manifolds in #MotorCortex with Sara Solla ✌️, one of the pioneers of the manifold modelling approach in #Neuroscience.

🌍 http://theoreticalneuroscience.no/thn36

#CompNeuro #ComputationalNeuroscience

Screenshot: Discussion of low-dimensional manifolds in motor cortex with Sara Solla.

There's a great talk by Juan Gallego on how low-dimensional #NeuralManifolds arise from biological constraints, remain invariant across states and inputs, and support cross-animal alignment. Examples span #HeadDirection rings, #gridcell tori, #MotorCortex prep vs movement, striatal timing dynamics, and C. elegans #behavior loops. Cool talk as it shows how #manifold-level structure can generalize across tasks and organisms.

🌍 https://www.youtube.com/watch?v=oxQyKByqDSU

#CompNeuro #Neuroscience #PopulationDynamics

🧠 New preprint by Codol et al. (2025): Brain-like #NeuralDynamics for #behavioral control develop through #ReinforcementLearning. They show that only #RL, not #SupervisedLearning, yields neural activity geometries & dynamics matching monkey #MotorCortex recordings. RL-trained #RNNs operate at the edge of #chaos, reproduce adaptive reorganization under #visuomotor rotation, and require realistic limb #biomechanics to achieve brain-like control.

🌍 https://doi.org/10.1101/2024.10.04.616712

#CompNeuro #Neuroscience

Fig. 2: Neural networks trained with RL or SL achieved high performance in controlling the effector .

🧠 New preprint by Kashefi et al. (2025): High-density #Neuropixels recordings in monkeys reveal compositional #NeuralDynamics in #MotorCortex. A posture subspace anchors fixed points, rotational dynamics link them to generate movement, and a uniform shift tracks trial state. Recurrent models show this geometry emerges only when controlling a full arm, suggesting posture-dependent control as a core principle:

🌍 https://www.biorxiv.org/content/10.1101/2025.09.04.674069v1

#Neuroscience #MotorControl #CompNeuro

Figure 3| Rotational dynamics
connect posture-specific fixed points
during reaching.
A) Hand trajectories and speed profiles
for six trial types involving reaches
between three diagonal targets. Colors
indicate reach direction.
B) Left: M1 Neural trajectories for each
reach condition. Dotted traces
represent center-out reaches. Each
trace begins at a black marker indicating
the start location, shaped as a plus,
square, or circle corresponding to trials
that began from the plus, square, or
circle target, respectively. Traces are
colored by reach direction, and arrows
indicate the go cue. Each trace ends in a
colored marker (plus, square, or circle)
representing the end target location.
Right: Same as left, but for the trial
types shown in panel A (right).
C) Neural trajectories projected onto
the top three principal components
(PCs) from a PCA fit across all 20
conditions. Each trace represents one
reach condition, colored by reach
direction. As in panel B, black markers
indicate start locations and colored
markers indicate end locations.
D–F) Same as panels A–C, but for
Monkey P

Movements can be initiated before or when one becomes aware of the intention. This study shows that spiking activity in human primary #MotorCortex coincides with onset of subjective intention, extending prior work on pre-motor & parietal #brain areas @PLOSBiology https://plos.io/4ivhobk

Neural recording and experimental setup. Top: T1-weighted magnetic resonance imaging (MRI) showing the overlap between arm/hand movement areas (from functional MRI) in primary motor cortex and the placement of the recording array as indicated by post-operative tomography. Bottom: Rendering of the experimental setup, where the BMI user (pixelated for privacy) viewed a clock with a single hand (red dot) performing a full cycle in 2,560 ms and had to indicate when he first intended to move, when he moved (action), or when tones occurred (effect).

What are the neural correlates of the multiple processes occurring during #sensorimotor #learning? This study reveals 3 distinct connectivity patterns in #MotorCortex associated with implicit learning, explicit learning & performance-tracking #PLOSBiology https://plos.io/4inwSPz

#PatrickHaggard - What is the #Problem with #FreeWill?

https://www.youtube.com/watch?v=b24jxQpLZsk

#Philosophy #PhilosophyOfFreeWill #Psychology #Neuroscience #Choice #Intention #Intentionality #Cortex #MotorCortex #Decision #Decisions #Mind #PhilosophyOfMind #StrongWill #WeakWill #CloserToTruth #RobertKuhn

Preserved neural dynamics across animals performing similar behaviour | Nature: https://www.nature.com/articles/s41586-023-06714-0

#Neuroscience #NeuralDynamics #MotorCortex

Different flavors of beta oscillation. @NougaretSimon @BjKilavik &co show that high & low beta rhythms co-reside in the #MotorCortex of macaques and have distinct, band-specific roles in movement control & spatio-temporal attention #PLOSBiology https://plos.io/3xBcpnT

Connectivity underlying #motorcortex activity during naturalistic goal-directed #behavior – #preprint by Finkelstein et al. (2023).

🌍 https://www.biorxiv.org/content/10.1101/2023.11.25.568673v1

#Neuroscience #NeuronNetworks #Learning

Fig. 1 | Neural activity in ALM during tongue-reaching

Mind-Body Connection Is Built Into Brain

Brain areas that control movement are plugged into networks that orchestrate thinking and planning, and control involuntary bodily functions. The findings provide a link between the body and the “mind” in the brain’s structure.

#Neuroscience #Brain #Neurology #BrainMap #MotorCortex #Homunculus
#SomatoCognitiveActionNetwork #SCAN
#Neuroimaging #fMRI

https://neurosciencenews.com/mind-body-brain-23049/

A somato-cognitive action network alternates with effector regions in motor cortex

#Neuroscience #Brain #Neurology #BrainMap #MotorCortex #Homunculus
#SomatoCognitiveActionNetwork #SCAN
#Neuroimaging #fMRI

https://www.nature.com/articles/s41586-023-05964-2

Famous ‘homunculus’ brain map redrawn to include complex movements

Textbook homunculus diagram depicts how the brain controls individual body parts — the revamp could improve treatments for brain injury.

#Neuroscience #Brain #Neurology #BrainMap #MotorCortex #Homunculus #Neuroimaging #fMRI

https://www.nature.com/articles/d41586-023-01312-6

Check out Janine’s new paper on TMS multi-pulse I-wave independent short-interval intracortical facilitating in press in JNeurophysiol by Hartwig Siebner, Mitsuaki Takemi, Anke Karabanov and Lasse Christiansen.
https://doi.org/10.1152/jn.00263.2022

Kesselheim et al. find that delivering two or more pulses at interstimulus intervals corresponding to the peaks of individual SICF curves - but also the trough between the 1st and 2nd peak - facilitate MEPs and reduce corticomotor threshold.

TMS bursts facilitate corticomotor excitability via two mechanisms: SICF-dependently via fast-conducting direct projections from M1-HAND to spinal motoneurons and SICF–independently probably through slower conducting indirect pyramidal tract projections.

We argue that an exclusive focus on I-wave periodicity is too narrow when aiming at understanding how TMS excites the precentral motor representations. The role of the I-wave independent facilitation in the control and development of skilled movement deserves more attention.

#tms #SICF #motorcortex #M1 #I-waves #I-wave #neuro #neuroscience #newpaper #paperThread #researchpaper

#arxivfeed :

"Monkey-to-human transfer of brain computer interface decoders"
https://www.biorxiv.org/content/10.1101/2022.11.12.515040v1

#neuroscience #neuro #brain #BCI #iBCI #EMG #WienerCascade #decoder #motorCortex

#MotorCortex

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