13. In summary: tolerance to self is a fixed, static system established at birth. It does not change dynamically during an individual’s life.

#immunology
#tolerance
#selfnonself
#science
#theory
#Foxp3
#Tregs

Why T Cell Tolerance Is Fixed from Birth

1. Unlike the innate immune system, which uses receptors to discriminate self from nonself based on biochemical features of the ligand (like LPS, foreign DNA, or foreign RNA)

#immunology
#tolerance
#selfnonself
#science
#theory
#Tregs