Post-exposure #prophylaxis with #favipiravir among #household close contacts to confirmed #COVID19 cases: A cluster-randomized trial (PEPfavi), https://etidiohnew.blogspot.com/2026/02/post-exposure-prophylaxis-with.html

+++ WAS IST DAS #PATENT6630507 +++

🌱 #Cannabinoids have been found to have #antioxidantproperties, unrelated to NMDA receptor antagonism. This new
found property makes cannabinoids useful in the #treatment and #prophylaxis of wide variety of #oxidationassociated
#diseases, such as #ischemic, #agerelated, #inflammatory & #autoimmunediseases.

https://venusproject.org/images/United-States-Patent-Cannabis-6630507.pdf

#Hanfwissen #Bundesregierung #Klingbeil #SPD #Cannabisklage #USA #Cannabis #Hanf #hemp #marijuana #Hanfgeschichten #Merz #Söder

last year's feature about the breakthrough in long-lasting #prophylaxis against #HIV-#AIDS is now in the #openArchive https://www.cell.com/current-biology/fulltext/S0960-9822(24)01500-8
#science #medicine #health #publicHealth

Post-exposure #prophylaxis regimen of #rabies monoclonal #antibody and #vaccine in category 3 potential exposure patients ..., https://etidiohnew.blogspot.com/2025/08/post-exposure-prophylaxis-regimen-of.html

Before the case was narrowed to the #AppointmentsClause issue, the lawsuit included a #religious objection to being required to cover pre-exposure #prophylaxis for #HIV. They claimed that such drugs "facilitate & encourage homosexual behavior, prostitution, sexual promiscuity & intravenous drug use."

#law #SCOTUS #medicine #HealthCare #ACA #insurance #PreventiveCare

Lenacapavir: this annual shot might protect against HIV infections
https://www.technologyreview.com/2025/03/14/1113225/annual-shot-protect-against-hiv

[Dec 2024] Drug lenacapavir 'breakthrough of year.' Could end HIV epidemic
https://mastodon.social/@persagen/113643639851357794
https://en.wikipedia.org/wiki/Lenacapavir

Promising results from an early-stage trial suggest that lenacapavir injections might offer long-lasting protection.

Comment: the value of basic science/biomedical research cannot be emphasized enough.

#HIV #AIDS #prophylaxis #lenacapavir
#GileadScience #PURPOSE1 #PURPOSE2 studies

Evaluation of #influenza #antiviral #prophylaxis for long-term care residents: a systematic review and meta-analysis, https://etidiohnew.blogspot.com/2025/03/evaluation-of-influenza-antiviral.html

Pre-exposure #antibody #prophylaxis protects #macaques from severe #influenza, https://etidiohnew.blogspot.com/2025/01/pre-exposure-antibody-prophylaxis.html

Drug lenacapavir 'breakthrough of year.' Could end HIV epidemic
https://www.npr.org/sections/goats-and-soda/2024/12/12/g-s1-37662/breakthrough-hiv-lenacapavir

* 1.3M new HIV infect./yr globally
* U.N. goal: end HIV/AIDS by 2030
* 2 groundbreaking clinical trials
* drug lenacapavir virt. elim. new HIV infections thru sex
* Science j. 2024 Breakthrough of Year
* admin. via 2x yearly injection

Lenacapavir: https://en.wikipedia.org/wiki/Lenacapavir

Epidemiology of HIV/AIDS
https://en.wikipedia.org/wiki/Epidemiology_of_HIV/AIDS

#HIV #AIDS #prophylaxis #lenacapavir
#GileadScience #PURPOSE1 #PURPOSE2 studies

I repeat: hypochlorous acid is a miracle. HOCl solution can apparently be nebulized and inhaled as a prophylactic (CW: animal testing)

"In this report, we establish through independent laboratories that the SARS-CoV-2 virus is rapidly inactivated by exposure to HOCl, as is poliovirus – a far more difficult virus to inactivate and often the gold standard for virucidal assessment. Inhalation of a microaerosolized fog of that same virucidal HOCl solution by rodents using the US EPA’s acute 4-hour inhalation toxicity protocol later provided observational, physiological, gross pathological, and histopathological evidence that showed pulmonary exposure of 52ppm HOCl to respiratory epithelium did not result in any difference when compared to control animals. Also reported are the chemical and antimicrobial characterizations of the HOCl microaerosols reportedly used as SARS-CoV-2 prophylaxis within the United States and elsewhere during the pandemic lockdown."

This also implies that you could stick it in a humidifier and disinfect the air of a space that someone infectious may have recently left, in addition to (or as an alternative to, if unavailable) air filtration

https://fortuneonline.org/articles/inhalation-of-microaerosolized-hypochlorous-acid-hocl-biochemical-antimicrobial-and-pathological-assessment.html

#SARSCoV2 #covid #covid19 #prophylactic #prophylactics #prophylaxis #PublicHealth #CovidIsNotOver

#Emergency #Use #Instructions (#EUI) for #Oseltamivir, #US #CDC: https://www.cdc.gov/bird-flu/hcp/emergency-use-oseltamivir/index.html

What to know: On July 19, 2024, CDC issued Emergency Use Instructions (EUI) for an #antiviral called oseltamivir, generic for brand name drug #Tamiflu, for #treatment or post-exposure #prophylaxis (#PEP) of #pandemic #influenza A viruses and novel influenza A viruses with pandemic potential.

Oral #Nirmatrelvir–Ritonavir as #Postexposure #Prophylaxis for #Covid19, N Engl J Med.: https://www.nejm.org/doi/full/10.1056/NEJMoa2309002

In this placebo-controlled trial, postexposure prophylaxis with nirmatrelvir–ritonavir for 5 or 10 days did not significantly reduce the #risk of symptomatic #SARS-CoV-2 infection. (Funded by Pfizer; ClinicalTrials.gov number, NCT05047601.)

HIV prevention drug found 100% effective in clinical trial
https://www.livescience.com/health/hiv/hiv-prevention-drug-found-100-effective-in-clinical-trial
#health #HIV #prevention #ClinicalTrial #lenacapavir #prophylaxis #PrEP #GileadSciences

#Antivirals for #PEP of #influenza: a systematic #review and network meta-analysis, MedRxIV, https://www.medrxiv.org/content/10.1101/2024.05.28.24307995v1

Post-exposure #prophylaxis with #zanamivir, #oseltamivir, #laninamivir or #baloxavir might reduce the #risk of symptomatic #zoonotic influenza after exposure to novel influenza A viruses associated with severe disease in infected humans.

#Epitopes of an #antibody that neutralizes a wide range of #SARS-CoV-2 #variants in a conserved subdomain 1 of the #spike protein, J Virol.: https://journals.asm.org/doi/full/10.1128/jvi.00416-24?af=R

Demonstrated identification of the neutralizing antibody that recognizes a conserved epitope implies basal contribution of such group of antibodies for #prophylaxis against #COVID19.

RT by @ECDC_EU: Check out our new issue with early data on effectiveness of monoclonal antibody against Respiratory syncytial virus #RSV from 🇪🇸

🗞️https://bit.ly/EUS296

#children #immunisation #prophylaxis #CCHF #vectors #Cdiff #encephalitis #HIV #publichealth

🐦🔗: https://nitter.cz/Eurosurveillanc/status/1755871682672120260#m

[2024-02-09 08:30 UTC]

#PersonalStudy #BookOfMormon https://www.churchofjesuschrist.org/study/scriptures/bofm/alma/49?lang=eng&id=p4#p4
Here is the common lesson about the importance of #preparation, #prophylaxis, and #SpiritualStrongholds. But two other amazements are first that #fortifying was apparently a novel idea to Moroni's inspiration, and also not thought of before by the Lamanites, who evidently did not know how to deal with it. Not too much later, fortifying will be a normal thing for both Nephites and Lamanites.

I meant "slightly annoying but useful #prophylaxis", obvs.

Less is more - don't add Vancomycin unless you need to in surgical prophylaxis.

(better, use teicoplanin, but many countries don't have it!)

#AMR #antibiotics #IDMastodon #infectiousdiseases #medicine #surgery #prophylaxis #MRSA

Trial of Vancomycin and Cefazolin as Surgical Prophylaxis in Arthroplasty

https://www.nejm.org/doi/full/10.1056/NEJMoa2301401?query=TOC&cid=NEJM%20eToc,%20October%2019,%202023%20DM2292852_NEJM_Non_Subscriber&bid=1868113537

Impaired neutralizing #antibody #efficacy of #tixagevimab-cilgavimab 150+150 mg as pre-exposure #prophylaxis against #Omicron #BA5. A real-world experience in booster vaccinated immunocompromised patients, J Clin Virol.: https://doi.org/10.1016/j.jcv.2023.105584 #reseach #science #medicine #mAbs #betacoronavirus #sarbecovirus #covid19