The next step in a great scientific adventure led by Marina Brasó Vives on amphioxus evolution: population genomics of a species with 3% heterozygosity! Read the thread and the preprint 😁 #amphioxus #EvoDevo #PopulationGenomics #MolecularEvolution
https://bsky.app/profile/mbrasovives.bsky.social/post/3mctuhgks7k2q

A new interpretation of Pikaia reveals the origins of the chordate body plan
https://doi.org/10.1016/j.cub.2024.05.026 #EvoDevo #fossil #paleontology #amphioxus

Very nice review on amphioxus biology https://elifesciences.org/articles/87028 #amphioxus #EvoDevo

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm

Euro #EvoDevo 2024 will include the following satellite meetings:
#Amphioxus
#Platynereis
#ArthropodEvolution (that's a lot of species for a satellite meeting!)
#FishEvolution
#Crustacean
https://ecoevo.social/@EED2024/110219897240880479

Now published in its final form: Parallel evolution of amphioxus and vertebrate small-scale gene duplications by Brasó-Vives et al
https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02808-6
#EvoDevo #EvolutionaryBiology #Genomics #Amphioxus #Chordate #ortholog #paralog #GeneDuplication

Above, my #introduction of interests. Here, who I am, what I do: a neuroscientist at the #MRCLMB and University of Cambridge, UK, studying the neural circuit basis of behavior, originally in #Drosophila but now also in #cephalopods (#pygmysquid #Idiosepius), the lancelet #Amphioxus and other animals. Our main approach: whole brain #connectomics with #vEM (volume electron microscopy) as the basis for computational modeling to guide neuronal activity perturbation and monitoring experiments with #optogenetics and #electrophysiology (#ephys for short).
Once upon a time I founded the #ImageJ -based #TrakEM2 software for image registration and neuronal arbor reconstruction and annotation, which spurred founding the #FijiSc (https://fiji.sc) image processing software, and later the #CATMAID web-based software for #connectomics.
Always open to inquires from prospective students and postdocs, and collaborations.