Lmst

»Nextcloud stellt ADA-Engine für massive Performance-Verbesserungen vor:
Mit der ADA-Engine bringt Nextcloud eine komplett neue Datenzugriffsarchitektur. Sie senkt die Serverlast drastisch und beschleunigt große Installationen.«

Ich nutze @nextcloud nur und habe keine Ahnung von deren Aufbau. Diese News erfreuen mich und hoffe, dass dies auch auswirkt ohne komplexe Server Einstellungen.

☁️ https://www.heise.de/news/Nextcloud-stellt-ADA-Engine-fuer-massive-Performance-Verbesserungen-vor-11168248.html

#nextcloud #webservices #datastorage #ada #adaengine #performance #datastorage

FYI: EzEsri, a public #GIS #data directory of #government #ArcGIS feature services https://ezesri.com/directory

#GISchat #geospatial #resources #WebServices #govtech #esri #mapping @esri @esrifederalgovt @esrislgov @arcgispro @arcgisonline @esritraining @urisa

We are happy to announce the release of #OSGeo #deegree #webservices version 3.6.6 which includes bug fixes and enhancements. Check out here https://github.com/deegree/deegree3/releases/tag/deegree-3.6.6

https://digitalforge.qa/website-services-qatar
#webservices

🧼 New post: Modernizing .NET – Part 7
.NET Core dropped Web References—here’s how to rebuild SOAP clients with dotnet-svcutil + typed wrappers.
🔗 https://medium.com/@michael.kopt/540dcc8352be
#DotNet #DotNetCore #DotNet8 #DotNet9 #DotNet10 #ASPNet #ASPNetCore #SOAP #WebServices #CSharp #SoftwareEngineering #LegacyCode

January 2026 WikiPathways update: 134 edits by 3 contributorsin the last month. More news at https://github.com/wikipathways/wikipathways-help/discussions/213 Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways

#bioinformatics #openscience #opensource

December 2025 WikiPathways release: 840 edits by 8 contributors and 9 new pathways (4 in screenshots). Accessible via #webservices, #rstats, #pathvisio and #cytoscape.

https://www.wikipathways.org/#download

#bioinformatics #elixirnl

WikiPathways WP5609: Key metabolic pathways in melanoma, glycolytic pathway, TCA cycle, glutamine metabolism, and oxidative phosphorylation, with potential therapeutic targets and inhibitors. Inhibitors targeting critical metabolic nodes are outlined in teal. This pathway is based on Figure 1 in Shen et al.

WikiPathways WP5606: Cis- and trans-acting regulators shape gene expression within the β-globin cluster. The LDB1 complex (LDB1/LMO2/GATA1/TAL1) binds both the locus control region (LCR) and globin promoters, promoting chromatin looping to activate these genes—interactions that may be influenced by cis-acting variants linked to HbS haplotypes. Across the HBB gene cluster and its surrounding regions, BCL11A and ZBTB7A (LRF) binding sites are present, represented by red and blue stars. Each of these transcription factors recruits its own NuRD complex. MYB regulates HbF expression directly and also indirectly through KLF1 and BCL11A. Repression of the HbF genes is indicated by dashed lines. Inspired by figure 1 in Habara et al. (2017).

WikiPathways WP5604: This pathway shows the molecular pathophysiology of sickle cell disease. (A) A single–nucleotide variant in the β-globin gene replaces glutamic acid with valine at position 6 of the β-globin chain. Upon deoxygenation, the resulting hemoglobin S (HbS) molecules polymerize into rigid fibers, driving erythrocyte sickling (clockwise). (B) Sickled cells cause impaired blood rheology and enhanced adhesion of erythrocytes to neutrophils, platelets, and the endothelium, leading to slowed or obstructed microvascular flow – called vaso-occlusion. Vaso-occlusion in turn promotes ischemia-reperfusion (I-R) injury (clockwise). (C) HbS polymer formation also leads to red cell membrane damage and hemolysis (counterclockwise), releasing cell-free hemoglobin (Hb) into circulation. Oxygenated Hb (Fe²⁺) contributes to endothelial dysfunction by consuming nitric oxide (NO) and producing nitrate (NO₃⁻) and methemoglobin (Fe³⁺). Hb can also undergo Fenton chemistry with H₂O₂, generating hydroxyl radicals (•OH) and additional methemoglobin. Methemoglobin (Fe³⁺) can degrade and release cell-free heme (counterclockwise), a potent erythrocyte-derived DAMP. (D) ROS production, TLR4 activation, NET formation, release of tissue- or cell-derived DAMPs, extracellular DNA, and other yet-undefined mediators generated by cell-free heme or I-R injury can induce sterile inflammation by activating the inflammasome in vascular and immune cells, leading to IL-1β release.

WikiPathways WP5607: Erythroid lineage cell differentiation transitions from hematopoietic stem cells (HSCs) through successive erythroid progenitors – burst-forming unit–erythroid (BFU-E), colony-forming unit–erythroid (CFU-E) – then proerythroblasts (proEB), basophilic erythroblasts (basoEB), polychromatic erythroblasts (polyEB), and orthochromatic erythroblasts (orthoEB), then and ultimately to reticulocytes, pyrenocytes, and mature red blood cells (RBCs). Stage-specific transcription factors (GATA1, GATA2), surface markers (CD34, CD45, CD71, CD235a), the onset of hemoglobin expression, and other factors are also depicted.

#Amazon #WebServices #AWS a dévoilé mardi de nouvelles fonctionnalités pour #AgentCore, sa #plateforme d' #agents #IA #AI. Des #contrôles de #sécurité et d'évaluation facilitent enfin le déploiement d' #agents #autonomes en #production. www.clubic.com/actualite-58...

Amazon révèle comment rendre l...

#Amazon #WebServices #AWS a dévoilé mardi de nouvelles fonctionnalités pour #AgentCore, sa #plateforme d' #agents #IA #AI. Des #contrôles de #sécurité et d'évaluation facilitent enfin le déploiement d' #agents #autonomes en #production.

https://www.clubic.com/actualite-589843-amazon-revele-comment-rendre-les-agents-ia-totalement-fiables-en-production.html

It's time for an upgrade. Switch to REST for a lighter load. ☕

When someone suggests using XML envelopes over JSON endpoints... Just take a REST, you deserve it. 😉

#WebServices #Protocol #APIDesign #RESTvsSOAP

My PikaPod is stuck loading. Feeling like I'm waiting centuries for the service to start up! It's the little IT moments that test your patience the most.

#PikaPods #SelfHosting #TechHumour #PodLoading #ServerLife #IT #OpenSource #AppHosting #TechStruggles #WaitingGame #Computers #DigitalAutonomy #Web #Technology #Troubleshooting #Patience #Humour #GeekLife #WebServices #Infra

A screenshot of the PikaPods "Pod is loading" page with a mouse graphic.

عطل عالمي في Cloudflare يتسبب في ارتباك واسع بمواقع التواصل والخدمات التقنية
https://pixelarab.com/2025/11/22/%d8%b9%d8%b7%d9%84-%d8%b9%d8%a7%d9%84%d9%85%d9%8a-%d9%81%d9%8a-cloudflare-%d9%8a%d8%aa%d8%b3%d8%a8%d8%a8-%d9%81%d9%8a-%d8%a7%d8%b1%d8%aa%d8%a8%d8%a7%d9%83-%d9%88%d8%a7%d8%b3%d8%b9-%d8%a8%d9%85%d9%88/
شهد عدد كبير من مستخدمي الإنترنت حول العالم، خلال يوم الثلاثاء، حالة ارتباك واضحة بعد ظهور مشكلات مفاجئة في مجموعة من المواقع والمنصات المعروفة. البداية كانت مع عطل أصاب خدمة Cloudflare، وهي إحدى أبرز الشركات المتخصصة في حماية الموا
#Ai #Cloudflare #CyberSecurity #DigitalPlatforms #InternetIssues #Outage #TechNews #WebServices #أخبار_التقنية #انقطاع_الخدمات #تقنية

November 2025 WikiPathways update: 686 edits by 6 contributors and 10 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #cytoscape.

Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways

#bioinformatics #openscience #opensource

New pathway, Caffeine in blood vessels (WP5601). In vascular smooth muscle, caffeine promotes relaxation by inhibiting myosin light-chain kinase (MLCK) through cAMP elevation and activating myosin light-chain phosphatase (MLCP), reducing myosin–actin interaction. As a nonselective adenosine receptor antagonist, caffeine blocks A₁/A₃ receptors (which normally lower cAMP) and A₂A/A₂B receptors (which normally raise cAMP), thereby altering adenylate cyclase activity. In endothelial cells, caffeine increases intracellular Ca²⁺, activating eNOS to produce nitric oxide (NO), which diffuses to smooth muscle and stimulates cGMP signaling, further promoting vasodilation. Inspired by Figure 1 in Kumar and Lipshultz, 2019.

New pathway, KCNQ2 and KCNQ3-related epilepsy (WP5599): Processes involved in KCNQ2 and KCNQ3-related epilepsies.

New pathways, GABA and glutamate signalling in epileptogenesis (WP5600): This pathway depicts the epileptogenic mechanisms involving GABA and glutamate signaling. It focuses on transporters and channel proteins that modulate action potential dynamics and their interacting partners, highlighting functional alterations that contribute to epilepsy pathogenesis.

This is my November Fedi reminder that I am a talented #Java developer looking for a developer position either remote, or based in Tampa, FL. I have some neat skills, like #CoreJava, #JavaEE, #Spring Frameworks, #WebServices, #Kafka, and many others. If you want to set up a call, I promise I will respond. (And I only ask you apply the same rule.)

Oh yeah, something-something-pumpkin-spice; now it's a November post.

#FediHire #fedijob #PumpkinSpice

‪🎙️ Python Bytes 455: Gilded Python and Beyond
https://pythonbytes.fm/episodes/show/455/gilded-python-and-beyond
with @brianokken and @mkennedy
#Python #CLIs #webservices #GC #Pets #Agentic #AI #TDD

⏳ Implementare un WebService SOAP con PHP
Come creare un servizio SOAP utilizzando esclusivamente PHP...

👉 https://www.selectallfromdual.com/blog/1656

#php #soap #webservices

October 2025 WikiPathways update: 129 edits by 10 contributors and 5 new pathways in the last month. Accessible via #webservices, #rstats, #pathvisio and #cytoscape. Supported by #awsopen. https://www.wikipathways.org/index.php/Download_Pathways

#bioinformatics #openscience #opensource

🤓 Oh, the joys of reading about how technology should be a festering mess of warts! Apparently, watching a #YouTube video is now the pinnacle of intellectual endeavor for those pondering the eternal mysteries of web services. 🤦‍♂️ The talk promises #insights on "htmx," but delivers a sermon on bridge-building instead—because what coder doesn't need architectural advice? 🏗️
https://entropicthoughts.com/you-want-technology-with-warts #techdebate #webservices #htmx #architecture #HackerNews #ngated

I'm busy finishing my presentation about my websites on geospatial webservices with data for Belgium. If you want to come and hear me talk about what that is and how and why I make these websites, you can hear me tell me all about it at FOSS4G Belgium this thursday in Brussels at 15h50 in the "Qleur Café" room. You can still get tickets on https://www.foss4g.be.

#FOSS4G #Belgium #GIS #Geospatial #webservices

Geospatial webservices: how to find what you're looking for

Unlock Odoo 18 Web Services for ultimate integration! Our guide reveals 5 secrets to mastering XML-RPC & JSON-RPC. Connect apps seamlessly. #Odoo18 #WebServices #APIIntegration #OdooTutorial #TechGuide #ERPIntegration

https://teguhteja.id/odoo-18-web-services-ultimate-integration-secrets/?utm_source=mastodon&utm_medium=jetpack_social

#WebServices

Client Info