SBGrid
2026-02-13

New Member Alert: In January, , Anne Marie Wehenkel along with the Image Analysis Hub, under the direction of Jean-Yves Tinevez at Institut Pasteur joined SBGrid. Welcome!!

2026-02-12

New Title Alert: Foundry- is a unified framework for protein design that provides tooling and infrastructure for using and training models including RFdiffusion3 (all-atom generative design), RosettaFold3 (structure prediction), and ProteinMPNN/LigandMPNN (inverse folding).

Learn more here: rosettacommons.github.io/found

#SBGrid #SBGridSoftware #StructuralBiology

2026-02-11

If you missed Alice-Roza Eruera's January webinar on Building CryoET Training Workflows Using the SBGrid Ecosystem, you can now find it on our YouTube channel.

Here: youtu.be/7nYke4ZoqEo

#SBGrid #Webinars #ScienceMatters

2026-02-11

Technical Notes: Personal Installation Credentials Users who currently only have access to the SBGrid software collection through a common site installation may also benefit from access to the collection on personally managed laptops or desktops in the laboratory or at home.


Register for personal credentials here: sbgrid.org/registration/regist
Learn more on our wiki: docs.sbgrid.org/installation/i
Contact us with additional questions accounts@sbgrid.org

2026-02-11

New Member Alert: James Chen from University of California, San Francisco joined SBGrid in January! Welcome.

2026-02-10

SBGrid's eLife paper received a citation in January from Bharti Singal, Ph.D. at Stanford University SLAC CryoEM Initiative contributing in Nature Magazine Chemical Engineering: A synthetic cell-free pathway for biocatalytic upgrading of formate from electrochemically reduced CO2.

Read more here: nature.com/articles/s44286-025

#SBGrid #ScienceMatters

2026-02-10

New Title Alert: ConSurf- is a bioinformatics tool designed for estimating the evolutionary conservation of amino and nucleic acid positions in protein, DNA, and RNA molecules.

Learn more here: github.com/Rostlab/ConSurf

#SBGrid #SBGridSoftware #StructuralBiology

2026-02-09

Join our software webinar on February 10th to hear from Alyssa Travitz of the Open Molecular Software Foundation, @index@news.omsf.io on Open Free Energy: An Open Source Ecosystem for Calculating Free Energies.

Tuesday, February 10, 2026 - 12:00pm ET
Alyssa Travitz
Senior Research Software Engineer, Open Molecular Software Foundation

Register here: sbgrid.org/webinars/

#SBGrid #Webinars #StructuralBiology

2026-02-06

New Member Alert: Javid Babak from University of California, San Francisco joined SBGrid in January. Welcome!

2026-02-06

We're pleased to welcome Cariuna Ellison of Fisk University !

Cariuna Ellison's highlight features a JCI Insight publication from the laboratory of Charles Sanders at Vanderbilt University in which the authors describe a small molecule that may change the trajectory of LQTS intervention research.

Read more here: medium.com/sbgrid-community-ne

Left: Most frequently observed orientation of VU0494372 docked to KCNQ1 rotated and zoomed, using KCNQ1-CaM in complex with ML277 (PDB 7XNK). Image adapted from Figure 6E. Right: Full view of the KCNQ1–CaM complex with ML277 bound shown in grey (PDB: 7XNK). Four subunits of each protein are present, with one ML277 ligand bound per subunit. Key binding residues for VU0494372, Thr312, Val334, Ser338, and Phe340, are highlighted in red. CC by SBGrid.
2026-02-05

SBGrid's eLife paper received a citation in January from Jason McLellan from The University of Texas at Austin in Nature Magazine Communications: Structure and immunogenicity of an engineered soluble prefusion-stabilized EBV gB antigen.

Read more here: nature.com/articles/s41467-025

#SBGrid #ScienceMatters

2026-02-05

New Title Alert: Calc_level_chimeraX- is a ChimeraX plugin to predict and visualize isosurface levels for 3D density maps. This tool is based on a 3D-CNN initially developed to predict the isosurface levels of 3D density maps, as required by SIREn.

Learn more here: github.com/mariacarreira/calc_

#SBGridSoftware #SBGrid #StructuralBiology

2026-02-04

New Title Alert: ThermoMPNN-D- is a Siamese neural network designed to predict stability changes from protein double point mutations.

Learn more here: github.com/Kuhlman-Lab/ThermoM

#SBGrid #SBGridSoftware #StructuralBiology

2026-02-04

Our January member tale features Jean-Philippe Julien from The Hospital for Sick Children in Toronto, who interrogates antibodies in the science of global heath, following their stories to guide interventions against infectious diseases like malaria.

Read more here: medium.com/sbgrid-community-ne

#SBGridTales #StructuralBiology #StayConnected

2026-02-03

If you missed Alice-Roza Eruera's January webinar on Building CryoET Training Workflows Using the SBGrid Ecosystem, we will have the video posted to the SBGrid YouTube channel soon.

You can subscribe at youtube.com/user/SBGridTV to receive alerts when new videos are added.

#SBGrid #Webinars #ScienceMatters

2026-01-30

SBGrid's eLife paper received a citation in December from Carsten Sachse from Forschungszentrum Jülich in Nature Magazine Communications: Structural organization of p62 filaments and the cellular ultrastructure of calcium-rich p62-enwrapped lipid droplet cargo.

Read more here: nature.com/articles/s41467-025

#SBGrid #ScienceMatters

2026-01-28

SBGrid's eLife paper received a citation in December from Catherine Drennan from Massachusetts Institute of Technology in Science Advances: How ATP and dATP reposition class III ribonucleotide reductase cone domains to regulate enzyme activity.

Read more here: science.org/doi/10.1126/sciadv

#SBGrid #ScienceMatters

2026-01-26

New Member Alert: In December, Paul Seidler from University of Southern California joined SBGrid. Welcome!!

2026-01-23

SBGrid's eLife paper received a citation in December from David Jeruzalmi from The City College of New York in Nucleic Acids Research:

Distinct quaternary states, intermediates, and autoinhibition during loading of the DnaB-replicative helicase by the phage λP helicase loader.

Read more here: academic.oup.com/nar/article/5

#SBGrid #ScienceMatters

2026-01-22

New Member Alert: from University of Pennsylvania joined SBGrid in December!. Welcome!!

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